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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNA4
All Species:
24.55
Human Site:
S603
Identified Species:
54
UniProt:
P22459
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22459
NP_002224.1
653
73288
S603
K
F
R
S
S
T
S
S
S
L
G
D
K
S
E
Chimpanzee
Pan troglodytes
XP_524797
575
63732
K526
R
S
N
S
T
L
S
K
S
E
Y
M
V
I
E
Rhesus Macaque
Macaca mulatta
XP_001088267
652
73147
S602
K
F
R
S
S
T
S
S
S
L
G
D
K
S
E
Dog
Lupus familis
XP_542545
666
74147
S616
K
F
R
S
S
T
S
S
S
L
G
D
K
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61423
654
73455
S604
K
F
R
S
S
T
S
S
S
L
G
D
K
S
E
Rat
Rattus norvegicus
P15385
655
73372
S605
K
F
R
S
S
T
S
S
S
L
G
D
K
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505719
2035
215303
S1985
K
F
R
S
S
T
S
S
S
L
G
E
K
S
E
Chicken
Gallus gallus
Q7T199
516
58965
Y467
V
I
V
S
N
F
N
Y
F
Y
H
R
E
T
E
Frog
Xenopus laevis
P22739
499
56683
A450
D
L
Q
K
S
R
S
A
S
T
L
S
K
S
D
Zebra Danio
Brachydanio rerio
XP_687427
641
71769
G589
K
F
K
G
S
P
S
G
S
S
L
G
D
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08510
655
74175
K605
Q
Q
Q
Q
N
G
F
K
Q
Q
Q
Q
Q
T
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.1
97.6
86.6
N.A.
95.5
96.4
N.A.
29.6
51.2
55.1
68.1
N.A.
52.2
N.A.
N.A.
N.A.
Protein Similarity:
100
68.1
97.6
90.2
N.A.
96.9
97.7
N.A.
30.8
62.6
63.8
79.4
N.A.
67.1
N.A.
N.A.
N.A.
P-Site Identity:
100
26.6
100
100
N.A.
100
100
N.A.
93.3
13.3
33.3
33.3
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
100
100
N.A.
100
100
N.A.
100
40
53.3
40
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
0
46
10
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
10
0
10
10
0
73
% E
% Phe:
0
64
0
0
0
10
10
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
10
0
10
0
0
55
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
64
0
10
10
0
0
0
19
0
0
0
0
64
10
0
% K
% Leu:
0
10
0
0
0
10
0
0
0
55
19
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
10
0
19
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
10
19
10
0
0
0
0
10
10
10
10
10
0
10
% Q
% Arg:
10
0
55
0
0
10
0
0
0
0
0
10
0
0
0
% R
% Ser:
0
10
0
73
73
0
82
55
82
10
0
10
0
64
0
% S
% Thr:
0
0
0
0
10
55
0
0
0
10
0
0
0
19
0
% T
% Val:
10
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
10
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _